Active Ingredient Devil's Claw (harpagophytum Procumbens Dc)

a plant genus of the family pedaliaceae. members contain harpagoside and are the source of extract ws 1531.

Source:

medlineplus herbs and supplements: devil's claw (harpagophytum procumbens dc)

Medical Condition	Uses based on scientific evidence	Grade*
lumbago	there are several human studies that support the use of devil's claw for the treatment of low back pain. however, most studies have been small with flaws in their designs, and many have been done by the same authors. therefore, although these results can be considered promising early evidence, additional well-designed trials are necessary before a firm conclusion can be reached. it is not clear how devil's claw compares to other therapies for back pain.	b
neoplasms	devil's claw is used to treat several types of pain, including osteoarthritis and low back pain. one case report indicates it may also be helpful for pain due to bone metastases. more research is needed in this area before a conclusion can be drawn.	c
osteoarthrosis unspecified whether generalized or localized	there is increasing scientific evidence suggesting that devil's claw is safe and beneficial for the short-term treatment of pain related to degenerative joint disease or osteoarthritis (8-12 weeks), it may be equally effective as drug therapies such as non-steroidal anti-inflammatory drugs like ibuprofen (advil, motrin ), and it may allow for dose reductions or stopping of these drugs in some patients. however, most studies have been small with flaws in their designs. additional well-designed	b

*Key to grades
A: Strong scientific evidence for this use;
B: Good scientific evidence for this use;
C: Unclear scientific evidence for this use;
D: Fair scientific evidence against this use;
F: Strong scientific evidence against this use.