Active Ingredient Horse Chestnut (aesculus Hippocastanum L.)

a plant genus of the family hippocastanaceae (or sapindaceae by some) that contains antimicrobial protein 1 and escin. a. hippocastanum is used in folk medicine for treating chronic venous insufficiency.

Source:

medlineplus herbs and supplements: horse chestnut (aesculus hippocastanum l.)

Medical Condition	Uses based on scientific evidence	Grade*
chronic venous hypertension without complications	chronic venous insufficiency (cvi) is a condition that is more commonly diagnosed in europe than in the united states and may include leg swelling, varicose veins, leg pain, itching, and skin ulcers. there is evidence from laboratory, animal, and human research that horse chestnut seed extract (hcse) may be beneficial to patients with this condition. studies report significant decreases in leg size, leg pain, itchiness, fatigue, and "tenseness." there is preliminary evidence that hcse may be as	a

*Key to grades
A: Strong scientific evidence for this use;
B: Good scientific evidence for this use;
C: Unclear scientific evidence for this use;
D: Fair scientific evidence against this use;
F: Strong scientific evidence against this use.