Active Ingredient Yohimbe Bark Extract (pausinystalia Yohimbe Pierre Ex Beille Rubiaceae)

the terms yohimbine, yohimbine hydrochloride, and yohimbe bark extract are related but not interchangeable. yohimbine is an active chemical (indole alkaloid) found in the bark of the pausinystalia yohimbe tree. yohimbine hydrochloride is a standardized form of yohimbine that is available as a prescription drug in the united states and has been shown in human studies to be effective in the treatment of male impotence. yohimbine hydrochloride has also been used for the treatment of sexual side

Source:

medlineplus herbs and supplements: yohimbe bark extract (pausinystalia yohimbe pierre ex beille rubiaceae)

Medical Condition	Uses based on scientific evidence	Grade*
disturbance of salivary secretion	studies report that yohimbine is able to increase saliva in animals and in humans. based on these few studies, yohimbine has been used for the treatment of dry mouth caused by medications, such as antidepressants. however, yohimbe bark extract may not contain significant amounts of yohimbine and therefore may not have these effects. more research is needed before a strong recommendation can be made.	c
impotence of organic origin	yohimbine hydrochloride is a prescription drug that has been shown in multiple human trials to effectively treat male impotence. yohimbine may also be a useful treatment option in orgasmic dysfunction. although yohimbine is present in yohimbe bark extract, levels are variable and often very low. therefore, although yohimbe bark has been used traditionally to reduce male erectile dysfunction, there is not enough scientific evidence to form a firm conclusion in this area.	c
nervous system complications	it is theorized that yohimbine may improve orthostatic hypotension (lowering of blood pressure with standing) or other symptoms of autonomic nervous system dysfunction. however, yohimbe bark extract may not contain significant amounts of yohimbine, and therefore may not have these proposed effects. more research is needed before a strong recommendation can be made.	c
other extrapyramidal diseases and abnormal movement disorders	yohimbine hydrochloride, a standardized form of yohimbine that is available as a prescription drug in the united states, has been suggested to treat sexual dysfunction due to ssri antidepressants. however, research in this area is limited, and more study is needed before a recommendation can be made. in addition, yohimbe bark extract may not contain significant amounts of yohimbine and therefore may not have these proposed effects.	c
other musculoskeletal symptoms referable to limbs	yohimbine combined with resistance training does not appear to alter body mass, muscle mass, or exercise performance.	d

*Key to grades
A: Strong scientific evidence for this use;
B: Good scientific evidence for this use;
C: Unclear scientific evidence for this use;
D: Fair scientific evidence against this use;
F: Strong scientific evidence against this use.